The Cytocompatibility of Silk Fibroin/Poly(ε-caprolactone) Electrospun Fibers
نویسندگان
چکیده
منابع مشابه
Electrospun silk fibroin/poly(lactide-co-ε-caprolactone) nanofibrous scaffolds for bone regeneration
BACKGROUND Tissue engineering has become a promising therapeutic approach for bone regeneration. Nanofibrous scaffolds have attracted great interest mainly due to their structural similarity to natural extracellular matrix (ECM). Poly(lactide-co-ε-caprolactone) (PLCL) has been successfully used in bone regeneration, but PLCL polymers are inert and lack natural cell recognition sites, and the su...
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Electrospun polymeric fibers have been investigated as scaffolding materials for bone tissue engineering. However, their mechanical properties, and in particular stiffness and ultimate tensile strength, cannot match those of natural bones. The objective of the study was to develop novel composite nanofiber scaffolds by attaching minerals to polymeric fibers using an adhesive material - the muss...
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Atomic force microscopes have become indispensable tools for mechanical characterization of nanoscale and submicron structures. However, materials with complex geometries, such as electrospun fiber networks used for tissue scaffolds, still pose challenges due to the influence of tension and bending modulus on the response of the suspended structures. Here we report mechanical measurements on el...
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Silk fibroin has attracted great interest in tissue engineering because of its outstanding biocompatibility, biodegradability and minimal inflammatory reaction. In this study, two kinds of biocomposites based on regenerated silk fibroin are fabricated by electrospinning and post-treatment processes, respectively. Firstly, regenerated silk fibroin/tetramethoxysilane (TMOS) hybrid nanofibers with...
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The functional properties of six distinct electrospun silk material groups were evaluated to assess conformational and biocompatible characteristics related to wound dressings. In a hydrated state, all six silk matrices exhibited absorption, water vapor transmission, oxygen permeation and enzymatic biodegradation suitable for full-thickness wound sites. Employing constrained drying techniques, ...
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ژورنال
عنوان ژورنال: Material Sciences
سال: 2013
ISSN: 2160-7613,2160-7621
DOI: 10.12677/ms.2013.36046